PROFESSIONAL SUMMARY

I am a motivated postgraduate researcher with a passion for problem-solving and a strong background in microbiology, molecular techniques, and data-driven research. My interests span antimicrobial resistance, bioinformatics, biotechnology, cell biology, public health, pharmacology, immunology, and child development. With experience in public health, pharmacology, bioinformatics, data science and microbiology and conducting interdisciplinary research, I am committed to advancing scientific knowledge and contributing to societal well-being through impactful research and innovation.

EDUCATION

PhD Biotechnology→ View Research Overview

University of Ghana, Accra, Ghana

2025 to date

Molecular Data for Infectious Disease

Institute of Tropical Medicine, Antwerp, Belgium

2025

MPhil Infection and Immunity

University of Cape Coast, Cape Coast, Ghana

01/2022 – 11/2024

Chemistry

University of Cape Coast, Cape Coast, Ghana

08/2016 – 07/2020

General Science

Sandema Senior High Technical School, Sandema, Ghana

11/2012 – 05/2015

SKILLS & COMPETENCIES

Digital & Data Tools

AI-Powered Web Development • R programming • Python • MySQL • Machine/Deep learning • Cloud computing • Power BI • Tableau • Minitab • Proficient in AI tools • Data analysis/visualization • SPSS • STATA • Graphic Design • Video/virtual conferencing • Project management • Cybersecurity awareness • GraphPad Prism • Origin Pro • QGIS/GIS

Professional Skills

Effective Communication • Team Collaboration • Project Coordination • Adaptability • Social media management • Email marketing and digital outreach • Digital document editing and formatting • Automation of workflows and tasks • Search engine optimization (SEO) • Spatial mapping • Conflict Resolution

Core Competencies

Molecular techniques • Bioinformatics • DNA extraction & sequencing • Protein-Protein Interaction analysis • Data science and analytics • HPLC • Mass spectroscopy • LAMP assay • Quantitative research • Qualitative research • Teamwork • Educational research

PROFESSIONAL EXPERIENCE

Research Assistant

Noguchi Memorial Institute for Medical Research

05/2024 – Date
  • Analyzing whole genome sequence data to identify genetic backgrounds, virulence factors, and antibiotic resistance genes
  • Monitoring infections in burn patients as part of routine antimicrobial surveillance
  • Researching the prevalence and resistance patterns of Staphylococcus aureus ST88

Research Assistant / Technical Officer – Central Region

University of Ghana, School of Public Health

02/2025 – 10/2025
  • Served as Technical Officer overseeing all field research operations for the Central Region
  • Implemented capture–recapture methodology for population size estimation
  • Conducted HIV, Hepatitis B and C, and Syphilis testing with ethical post-test counselling

Research Assistant – Unpaired Care Work Project

Centre for Learning and Childhood Development, Ghana

10/2024 – 11/2024
  • Collected quality survey data using KoboCollect
  • Maintained proper management of research files and consent forms
  • Adhered to ethical guidelines and confidentiality requirements

Project Statistician

Language of Education Project, UCC, Ghana

07/2023 – 08/2024
  • Designed and maintained a functional project website
  • Created impactful visual representations of data findings
  • Provided statistical expertise for informed decision-making

Research Assistant and Project Statistician

PROMPT-Ghana Project on Child Development

03/2024 – 11/2024
  • Analysed app pilot data to evaluate usability and effectiveness
  • Generated statistical reports summarizing pilot study findings
  • Analysed feedback from children to identify app improvements

Research Assistant

Noguchi Memorial Institute for Medical Research

02/2023 – 12/2023
  • Worked as senior bioinformatician and lead data analyst
  • Identified resistant/virulent genes using bioinformatics tools
  • Conducted antimicrobial susceptibility tests using Kirby Bauer method

Research Assistant – MEN'S Project

School of Public Health, University of Ghana

09/2022 – 05/2023
  • Analysed and interpreted data to provide actionable insights
  • Conducted interviews and surveys at various study settings
  • Prepared weekly progress reports for the Principal Investigator

Teaching Assistant

University of Cape Coast, Chemistry Department

09/2020 – 08/2021
  • Responsible for undergraduate organic and physical chemistry lab sections
  • Conducted tutorials and marked assignments with detailed feedback
  • Assisted supervisors with teaching activities in chemistry

KEY PROJECT

Antimicrobial Resistance (AMR) Surveillance Data System – Ghana

System Developer / Data Analyst | 2025

Designed and implemented a centralized data surveillance system to support antimicrobial resistance monitoring across reference laboratories and sentinel sites in Ghana.

Tools: Python, KoboToolbox, Google Sheets, Dashboard Analytics, Data Validation Systems

PUBLICATIONS

CONFERENCES & WORKSHOPS

  • 14th Convention for Biomedical Research, Ghana Conference - NMIMR28/08/2024 – 30/08/2024
  • Introduction to Biomedical and Health Research (B-HERE) – Zoom cloud02/05/2023 – 04/05/2023
  • Biosafety, Biosecurity and Good Laboratory Practices02/2023
  • Strengthening and building research capacities using LAMP technique as a prototype for detecting pathogens13/02/2023 – 16/02/2023
  • Laboratory Management and Safety Workshop01/11/2020 – 05/11/2020
  • Workshop on data analysis using SPSS and R Programming08/08/2016 – 12/08/2016

LEADERSHIP

President of Builsa Students Union - UCC (2019)

  • Co-ordinate the overall work of the Students' Union
  • Manage the SU budget and associated finances
  • Represent the Students Union at appropriate forums

PROFESSIONAL MEMBERSHIPS

  • Convention For Biomedical Research Ghana (CoBREG) (2023 – present)
  • American Society of Microbiology - USA (2023 – present)
  • European Society of Clinical Microbiology and Infectious Diseases (2024 – present)

REFERENCES

Prof. Nicolas T.K.D. Dayie

University of Ghana Medical School

ntkddayie@ug.edu.gh

(+233) 0208449415

Prof. Dorcas Obiri Yeboah

University of Cape Coast, School of Medical Sciences, Department of Microbiology and Immunology

dobiri-yeboah@ucc.edu.gh

(+233) 244527387

Dr. Ewura Seidu Yahaya

University of Cape Coast, School of Medical Sciences, Department of Pharmacology

e.s.yahaya@ucc.edu.gh

(+233) 244620412

Dr. Nana Ama Amissah

Noguchi Memorial Institute for Medical Research, Department of Bacteriology

namissah@noguchi.ug.edu.gh

(+233) 549420298

PHD RESEARCH OVERVIEW

🎯 Research Topic

CRISPR-Cas13a–Based Targeting of Antimicrobial Resistance Determinants in Multidrug-Resistant Klebsiella pneumoniae and Escherichia coli Isolates from Food-Producing Livestock in Ghana

📚 Background

Antimicrobial resistance (AMR) is a growing threat to public health, food safety, and animal health worldwide. In Ghana, food-producing livestock increasingly serve as reservoirs of multidrug-resistant (MDR) bacteria, particularly Klebsiella pneumoniae and Escherichia coli. These organisms are commonly associated with zoonotic and foodborne infections and are capable of transferring resistance genes to humans through direct contact, contaminated animal products, and environmental exposure. The widespread use of antibiotics in animal production has accelerated the emergence and spread of resistance genes that compromise the effectiveness of commonly used antimicrobials. Innovative and targeted approaches are therefore required to complement existing AMR control strategies, especially within the One Health framework.

⚠️ Statement of the Problem

Despite national and regional efforts to address AMR, surveillance and intervention strategies in Ghana remain largely focused on detection rather than targeted mitigation of resistance at its source. MDR K. pneumoniae and E. coli circulating in food-producing livestock harbor clinically important resistance determinants that can enter the human population through the food chain. However, there is limited laboratory-based research in Ghana exploring advanced, gene-targeted approaches for addressing resistance in animal reservoirs. This gap limits the development of effective, context-specific solutions to interrupt zoonotic transmission of AMR.

🎯 Research Objectives

  1. To isolate and characterize multidrug-resistant K. pneumoniae and E. coli from food-producing livestock.
  2. To determine phenotypic resistance profiles and identify key antimicrobial resistance genes.
  3. To design CRISPR-Cas13a guide RNAs targeting selected resistance determinants.
  4. To evaluate the ability of CRISPR-Cas13a systems to silence resistance genes and restore antibiotic susceptibility in vitro.
  5. To assess biosafety, genetic stability, and potential off-target effects of the CRISPR-Cas13a approach.

🌍 Contribution to UN Sustainable Development Goals

SDG 3
Good Health & Well-being
Addressing AMR threats to disease treatment
SDG 2
Zero Hunger
Improving food safety & livestock health
SDG 12
Responsible Consumption
Prudent antimicrobial use in food production

💡 Significance of the Study

This study will generate laboratory-based evidence on AMR in zoonotic and foodborne pathogens from livestock, supporting One Health–driven AMR surveillance and control strategies in Ghana. By exploring CRISPR-Cas13a as a precision tool for targeting resistance genes, the research introduces innovative approaches that may complement conventional antimicrobial stewardship efforts. The findings are expected to inform policy, strengthen research capacity, and contribute to national and regional AMR action plans.

🔬 Key Research Areas & Techniques

CRISPR-Cas13aAntimicrobial ResistanceMolecular BiologyGenomicsOne HealthBioinformaticsMicrobiologyGene SilencingBiosafety AnalysisWhole Genome Sequencing

🤝 Sponsorship & Collaboration Opportunities

The successful execution of this PhD research depends on access to advanced molecular biology and genomics facilities. I am actively seeking research sponsorship, institutional partnerships, and laboratory hosting opportunities—locally or internationally—to support sequencing, CRISPR-related experiments, and biosafety analyses. Collaborative laboratories and funding partners will play a critical role in enabling this work and advancing shared goals in AMR and One Health research.

📈 Expected Outcomes & Impact

  • Novel insights into AMR prevalence in Ghanaian livestock populations
  • Proof-of-concept for CRISPR-Cas13a-based resistance gene silencing
  • Contribution to One Health AMR surveillance frameworks
  • Policy recommendations for antimicrobial stewardship in agriculture
  • High-impact peer-reviewed publications and conference presentations
  • Strengthened regional research capacity in advanced molecular techniques

📬 Contact for Research Collaboration

Jesse Azebiik Anak

PhD Candidate, Biotechnology

University of Ghana, Accra

📧 jesseanak98@gmail.com

📱 (+233) 559759592

📍 Central Region, Cape Coast, Ayensu

Open to research collaborations, funding partnerships, and laboratory hosting opportunities. Let's work together to combat antimicrobial resistance.

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